A few years ago, work was published which showed that under certain conditions, some PARPs can modify RNA with ADP-ribose in vitro. Many questions were left unanswered: can all PARPs do this? Do they modify RNA in cells? What is the function of RNA ADP-ribosylation, how does it influence the modified molecules? We were intrigued... Continue Reading →
Available PhD position
We are looking for a PhD candidate to strengthen our team starting Autumn 2022! More details about the project are available below, or you can also get in touch with informal inquiries. phd-position-summer-2022Download
How to visualise ADP-ribosylation
We are studying the modification of proteins with ADP-ribose. Quite recently, reagents have been developed to visualise this. While doing some experiments, we quickly realised that not all detection reagents are equally well suited for all methods and substrates. Therefore we decided to cross-validate the available reagents and tested them on a range of substrates;... Continue Reading →
Student positions to study ADP-ribosylation in cancer and viral infection
We are recruiting one or two master/medical PhD students! Below are global outlines of possible research projects, which can be further developed according to students interests. One project has a more translational aspect and is well suited for a medical PhD student. PARP1 is utilised as drug target in for example BRCA1 negative breast cancer... Continue Reading →
Two PhD positions available
We currently have two open PhD student positions, funded by the DFG for three years. You can find the essentials on jobRxiv or a more detailed PDF as download available below. 202110-student-job-advertDownload
Merry Christmas and Happy New Year!
This year, we have closed the lab a bit earlier than usual. The Netherlands, where some of us live, are in a lockdown since the 14th, Germany followed a day later. We've frozen down our cells, we've cleaned up our benches and closed the door behind us. Hopefully we'll be back somewhere in January -... Continue Reading →
Long time, no see!
We have created this website quite a while ago, forgot all about its existence and now dragged it out from under the dust. Expect more updates soon!
Gülcans first day!
This is the excerpt for your very first post.